Physical activity, vasomotor endothelial function, and arterial stiffness

Arterial Stiffness and Endothelial Function in Patients With -Thalassemia Major

Background—Increased iron store has been linked to risk of cardiovascular disease. Structural alterations of arteries in -thalassemia major patients and in vitro functional disturbance of vascular endothelial cells by thalassemic serum have been described. We sought to determine whether arterial stiffness and endothelial function are altered in vivo. Methods and Results—Thirty thalassemia patie...

Arterial stiffness and endothelial function: key players in vascular health.

Functional assessment of the blood pressure waveform helps us to obtain an estimation of the arterial stiffness or its converse, arterial elasticity.1 Several epidemiological studies have clearly demonstrated that arterial stiffness is a significant predictor of cardiovascular disease incidence in the general population.2 There is clear evidence now that decreased arterial elasticity or increas...

Arterial Stiffness and Endothelial Dysfunction

The influence of dialytic modality on arterial stiffness, pulse wave reflections, and vasomotor function.

BACKGROUND Measurements of aortic stiffness [aortic pulse wave velocity (PWV) and augmentation index (Alx)] have been established as powerful predictors of survival on hemodialysis (HD). Abnormal endothelial-dependent and endothelial-independent vascular reactivity and increased arterial stiffness are commonly described in HD patients. There is, however, a lack of information on the comparative...

Arterial stiffness and kidney function.

The vascular hallmark of subjects with end-stage renal disease undergoing hemodialysis is increased aortic stiffness, a phenomenon independent of mean arterial blood pressure, wall stress, and standard cardiovascular risk factors such as plasma glucose, cholesterol, obesity, and smoking. These observations suggest that subtle links might associate arterial stiffness and kidney function in normo...